Maternal and Child Nutrition
Research is dedicated to elucidate determinants of survival and morbidity, with major emphasis on development of interventions for reducing child mortality and promoting growth and development.
Safety and efficacy of Kangaroo Mother Care on Neonatal Mortality and Mortality in Low Birth Weight Infants
Problem: Interventions are necessary for reduction of morbidities, mortality and growth failure in preterm and low birth weight babies. Formative research has proven the feasibility and acceptability of community-initiated KMC [BMC Public Health. 2018 Mar 2;18(1):307] but its mortality impact in home-based programs is not established.
Intervention: Assess the safety and efficacy of community-initiated Kangaroo Mother Care (KMC) in a randomised controlled trial involving 8400 infants.
Impact: Will enable to generate evidence on the feasibility, safety and efficacy of community-initiated KMC to enable development of WHO guidelines and national policies.
Impact of Kangaroo Mother Care on Linear Growth, Infection Reduction, Breast Milk Properties and Underlying Biological Pathways, in Low Birth Weight Infants
Problem: Lack of knowledge on pathways through which KMC reduces mortality or promotes growth
Intervention: Assess impact of KMC on linear growth, possible serious bacterial infection, breast milk quantity and quality, skin barrier function and establishment of beneficial gut microbiome in LBW infants
Impact: Will facilitate in elucidating some of the pathways by which community initiated KMC may produce beneficial health effects. This evidence will convince caregivers about the importance of KMC.
Association between Maternal Malnutrition and Lactation Quality in India
Problem: Poor nutritional status (low body mass index and anemia) of lactating mothers contributes to suboptimal lactation performance causing growth faltering in children as their nutrient requirements are not met.
Intervention: Use an innovative stable isotope methodology to measure maternal body composition and breast milk output. Maternal nutritional status assessed through anthropometric measurements (height, weight, mid-upper- arm and calf circumference, triceps and subscapular skinfolds), micronutrient status (serum analysis of key nutrients) and maternal dietary intake (24 hr recall and food frequency). Breastmilk macronutrients, micronutrients, immunological or inflammatory profiles and infants’ intestinal permeability will also be analyzed.
Impact: This innovative research will fill critical knowledge gaps and inform the design of future interventions to reduce growth faltering in the first 6 months of life.
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